Bio-efficiency
Compiled by Walter Sorochan
This information has not been approved by FDA:  Read  Disclaimer  

Bio-efficiency refers to how fast nutrients and silver are absorbed into the blood and made available to the body: This process can be illustrated simulating grapes as silver. Given equal size of volume [ aggregate volume ] of both the large and small grapes, smaller volume size yields greater surface area for silver absorption and activity. That is shown in the illustration below where you have two volumes of grapes. The volume, represented by the red grapes here, is the same on both sides. You have small molecules with small grapes on the right side and the large molecules with large grapes on the left side. The volume is the same. The surface area to volume ratio is obviously much greater among the small grapes on the right side, and silver bioactivity comes from that - bioactivity is just that simple. A greater absorption area!

surface area
Image source: David B. Van Wyck, iron absorption

Surface area increases while the volume remains the same: Primary determinants of silver bioactivity are not the total molecular weight, but the size of the core [ volume ] and the surface area to volume ratio. That is to say, the smaller the silver item, the faster it is absorbed into the blood stream and the sooner it acts on germs
 
References:
Van Wyck David V., "Characteristics of available iron products." ANNA CE Satellite Symposium - New Orleans, Louisiana, October 17, 2004.

Merick manual:   Drug Absorption

"Small molecules tend to penetrate membranes more rapidly than larger ones.
Whether a drug is acidic or basic, most absorption occurs in the small intestine because the surface area is larger and membranes are more permeable."